Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | CA1 | P00915 | 4/20 | 0.72 |
| ▸ | CA2 | P00918 | 4/20 | 0.72 |
| ▸ | CA4 | P22748 | 4/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | CA12 | O43570 | 3/20 | 0.72 |
| ▸ | CA3 | P07451 | 3/20 | 0.72 |
| ▸ | CA6 | P23280 | 3/20 | 0.72 |
| ▸ | CA5A | P35218 | 3/20 | 0.72 |
| ▸ | CA7 | P43166 | 3/20 | 0.72 |
| ▸ | CA9 | Q16790 | 3/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.72 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | DPP4 | P27487 | 2/20 | 0.72 |
| ▸ | BACE1 | P56817 | 2/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422777 | 1.00 | KDM4E (0.72) | KDM4ECA1CA2CA4HSD17B10 | |
| SCHEMBL6644081 | 0.89 | KDM4E (0.68) | KDM4ECA1CA2CA4HSD17B10 | |
| SCHEMBL6640901 | 0.89 | KDM4E (0.68) | KDM4ECA1CA2CA4HSD17B10 | |
| SCHEMBL8746656 | 0.84 | KDM4E (0.60) | KDM4ECA1CA2CA4HSD17B10 | |
| SCHEMBL8746658 | 0.84 | KDM4E (0.60) | KDM4ECA1CA2CA4HSD17B10 | |
| Caffeic Acid SCHEMBL7064846 | 0.84 | KDM4E (1.00) | KDM4ECA1CA2CA4HSD17B10 | |
| Caffeic Acid SCHEMBL23358 | 0.84 | KDM4E (1.00) | KDM4ECA1CA2CA4HSD17B10 | |
| Caffeic Acid SCHEMBL1262229 | 0.84 | KDM4E (1.00) | KDM4ECA1CA2CA4HSD17B10 | |
| Caffeic Acid SCHEMBL21114743 | 0.84 | KDM4E (1.00) | KDM4ECA1CA2CA4HSD17B10 | |
| Caffeic Acid SCHEMBL30501140 | 0.84 | KDM4E (1.00) | KDM4ECA1CA2CA4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644232-B1 | Free radical cured rubber | GOODYEAR TIRE & RUBBER (US) | 1997-03-05 | — | — | EP | claimed |
| EP-0644232-A1 | Free radical cured rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-03-22 | — | — | EP | claimed |
| US-5310811-A | Abrasion resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-05-10 | — | — | US | claimed |
| US-8080603-B2 | Low hysteresis rubber elastomer | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2011-12-20 | — | — | US | disclosed |
| US-20100056686-A1 | LOW HYSTERESIS RUBBER ELASTOMER | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2010-03-04 | — | — | US | disclosed |
| US-20100012241-A1 | CUSHION GUM | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2010-01-21 | — | — | US | disclosed |
| EP-2114696-A1 | LOW HYSTERESIS RUBBER ELASTOMER | Societe de Technologie Michelin (FR) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008079726-A1 | CUSHION GUM | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008079107-A1 | LOW HYSTERESIS RUBBER ELASTOMER | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2008-07-03 | — | — | WO | disclosed |
| EP-0644232-B1 | Free radical cured rubber | GOODYEAR TIRE & RUBBER (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0644232-A1 | Free radical cured rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5310811-A | Abrasion resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-05-10 | — | — | US | disclosed |