SCHEMBL3422882

SCHEMBL3422882

O=S(=O)(F)F.O=S(=O)(O)F

nearest known ligand 0.89

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.89
TDP1 Q9NUW8 1/20 0.89
CA5A P35218 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
CA2 P00918 2/20 0.46
CA1 P00915 1/20 0.42
NT5E P21589 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.32
BLM P54132 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29818845 0.94 TSHR (1.00) TSHRTDP1CA5ACA5BCA2
SCHEMBL1938 0.94
SCHEMBL6223954 0.89
SCHEMBL8376424 0.89
SCHEMBL8378298 0.89
Methane SCHEMBL9362880 0.89
Lithium SCHEMBL929003 0.89 TSHR (0.89) TSHRTDP1CA5ACA5BCA2
SCHEMBL8377677 0.89
SCHEMBL8379533 0.89
SCHEMBL6123214 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2209156-A1 Composite membrane and method for making General Electric Company (US) 2010-07-21 EP claimed
US-20100167100-A1 COMPOSITE MEMBRANE AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY 2010-07-01 US claimed
US-20120225371-A1 IONOMER FOR ALKALINE FUEL CELL LOS ALAMOS NATIONAL SECURITY, LLC (US) 2012-09-06 US disclosed
EP-2209156-A1 Composite membrane and method for making General Electric Company (US) 2010-07-21 EP disclosed
US-20100167100-A1 COMPOSITE MEMBRANE AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY 2010-07-01 US disclosed