Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.56 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.49 |
| ▸ | BCL2 | P10415 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422932 | 1.00 | MCL1 (0.56) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL3422944 | 1.00 | MCL1 (0.56) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL19425343 | 0.93 | MCL1 (0.58) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL13461491 | 0.92 | MCL1 (0.52) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL3419381 | 0.90 | BCL2 (0.55) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL3419383 | 0.90 | BCL2 (0.55) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL3419387 | 0.90 | BCL2 (0.55) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL3425202 | 0.88 | MCL1 (0.62) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL19425335 | 0.87 | MCL1 (0.72) | MCL1BAK1ADAMTS5BCL2PTPN1 | |
| SCHEMBL3421035 | 0.87 | MCL1 (0.52) | MCL1BAK1ADAMTS5BCL2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024783-A1 | BIARYLRHODANINE AND PYRIDYLRHODANINE COMPOUNDS AND THEIR USE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-03-04 | — | — | WO | disclosed |