Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | FASN | P49327 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432035 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL5688911 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL16149412 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL29403468 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL5688908 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL10538624 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL20866020 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL21638328 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL20866021 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL16149413 | 1.00 | TSHR (0.61) | TSHRALDH1A1FASNFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071565-B | Tricyclic heterocyclic derivatives | 默克专利股份公司 | 2022-05-10 | — | — | CN | disclosed |
| EP-3464295-B1 | TRICYCLIC HETEROCYLIC DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-02-05 | — | — | EP | disclosed |
| EP-2245014-A1 | UREA DERIVATIVES OF BENZOMORPHANES AND RELATED SCAFFOLDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | Boehringer Ingelheim International GmbH (DE) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009100872-A1 | UREA DERIVATIVES OF BENZOMORPHANES AND RELATED SCAFFOLDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-20 | — | — | WO | disclosed |