SCHEMBL3423356

SCHEMBL3423356

CCCCCNC(=O)OO

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.69
ACHE P22303 8/20 0.57
CASP2 P42575 1/20 0.52
MGLL Q99685 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3899913 0.98 EPHX1 (0.73) EPHX1ACHECASP2
SCHEMBL28524618 0.98 EPHX1 (0.73) EPHX1ACHECASP2
SCHEMBL28747970 0.98 EPHX1 (0.73) EPHX1ACHECASP2
SCHEMBL3462778 0.93
SCHEMBL443246 0.84 EPHX1 (0.95) EPHX1ACHECASP2
SCHEMBL851201 0.83
SCHEMBL3910901 0.82 EPHX1 (1.00) EPHX1ACHECASP2MGLL
SCHEMBL1616893 0.82 EPHX1 (1.00) EPHX1ACHECASP2MGLL
SCHEMBL717504 0.82 EPHX1 (1.00) EPHX1ACHECASP2MGLL
SCHEMBL13387440 0.82 EPHX1 (1.00) EPHX1ACHECASP2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105709229-A Novel lipids and compositions for the delivery of therapeutics 阿尔尼拉姆医药品有限公司 2016-06-29 CN disclosed
CN-102361650-B Lipids and compositions for delivery of therapeutic agents ALNYLAM PHARMACEUTICALS, INC. (US) 2016-04-20 CN disclosed
CN-105152939-A Lipids and compositions for the delivery of therapeutics ALNYLAM PHARMACEUTICALS INC 2015-12-16 CN disclosed
CN-104873464-A Improved lipid formulation ALNYLAM PHARMACEUTICALS INC 2015-09-02 CN disclosed
CN-102281899-B Lipids and compositions for delivery of therapeutic agents ALNYLAM PHARMACEUTICALS INC 2015-07-15 CN disclosed
CN-102625696-B Improved lipid formulations ALNYLAM PHARMACEUTICALS INC 2015-06-03 CN disclosed
CN-102105496-A Method of making carbamate functional materials BASF CORP 2011-06-22 CN disclosed
EP-2197921-A1 METHOD OF MAKING CARBAMATE FUNCTIONAL MATERIALS BASF Coatings GmbH (US) 2010-06-23 EP disclosed
WO-2009035667-A1 METHOD OF MAKING CARBAMATE FUNCTIONAL MATERIALS BASF CORPORATION (US) 2009-03-19 WO disclosed
EP-1362074-B1 CARBAMATE FUNCTIONAL POLYMERS AND OLIGOMERS BASF CORP (US) 2009-02-18 EP disclosed
US-6710138-B2 NONDEFORMING, SPRAYABLE, CHEMICAL RESISTANCE; CURABLE POLYURETHANES BASF CORPORATION 2004-03-23 US disclosed
EP-1362074-A1 CARBAMATE FUNCTIONAL POLYMERS AND OLIGOMERS BASF CORPORATION (US) 2003-11-19 EP disclosed
US-20030144429-A1 Carbamate functional polymers and oligomers OHRBOM WALTER H (US) 2003-07-31 US disclosed
US-6541577-B2 High solids coatings BASF CORPORATION 2003-04-01 US disclosed
US-20020147279-A1 Carbamate functional polymers and oligomers BASF CORPORATION 2002-10-10 US disclosed
WO-2002046261-A1 CARBAMATE FUNCTIONAL POLYMERS AND OLIGOMERS BASF CORPORATION, PLEASE SEE GENERAL APPOINTMENT OF REPRESENTATIVE (US) 2002-06-13 WO disclosed