Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18284760 | 0.82 | SLC6A2 (0.63) | SLC6A2ADRA2CSLC6A4SLC6A3MEN1 | |
| SCHEMBL28352389 | 0.77 | SLC6A2 (0.73) | SLC6A2ADRA2CSLC6A4SLC6A3MEN1 | |
| SCHEMBL27461070 | 0.77 | SLC6A2 (0.60) | SLC6A2ADRA2CSLC6A4SLC6A3MEN1 | |
| SCHEMBL27971252 | 0.75 | SLC6A2 (0.55) | SLC6A2ADRA2CSLC6A4SLC6A3CYP2D6 | |
| SCHEMBL14595288 | 0.74 | SLC6A2 (1.00) | SLC6A2ADRA2CSLC6A4SLC6A3HRH1 | |
| SCHEMBL6469426 | 0.74 | SLC6A2 (1.00) | SLC6A2ADRA2CSLC6A4SLC6A3HRH1 | |
| SCHEMBL6438236 | 0.74 | SLC6A2 (1.00) | SLC6A2ADRA2CSLC6A4SLC6A3HRH1 | |
| SCHEMBL8283440 | 0.74 | SLC6A2 (1.00) | SLC6A2ADRA2CSLC6A4SLC6A3HRH1 | |
| SCHEMBL14202964 | 0.73 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3MEN1LMNA | |
| SCHEMBL14203047 | 0.73 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068257-A1 | IMIDAZOPYRAZINE SYK INHIBITORS | CGI PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | WO | disclosed |