Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | PTGIR | P43119 | 2/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423126 | 0.92 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3434387 | 0.86 | PTGDR2 (0.56) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3429070 | 0.86 | PTGDR2 (0.59) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3432140 | 0.84 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL153736 | 0.84 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL17387610 | 0.84 | PTGDR2 (0.56) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3427629 | 0.83 | PTGDR2 (0.61) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3412389 | 0.82 | PTGDR2 (0.56) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL27800144 | 0.80 | PTGDR2 (0.55) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL138775 | 0.79 | PTGDR2 (0.75) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245002-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009099901-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |