Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10334581 | 0.89 | KCNN4 (0.53) | KCNN4SRCCES1TSHRMAPT | |
| SCHEMBL10334562 | 0.89 | KCNN4 (0.53) | KCNN4SRCCES1MAPTKMT2A | |
| SCHEMBL9292634 | 0.85 | KCNN4 (0.49) | KCNN4MAPTKMT2AMEN1OPRM1 | |
| SCHEMBL10334711 | 0.85 | KCNN4 (0.49) | KCNN4HDAC6NPC1RAB9ACYP1A2 | |
| SCHEMBL9292029 | 0.83 | KCNN4 (0.50) | KCNN4SRCCES1NPC1MAPK1 | |
| SCHEMBL340836 | 0.83 | KCNN4 (0.52) | KCNN4SRCCES1TSHRMAPT | |
| SCHEMBL3910744 | 0.82 | KCNN4 (0.48) | KCNN4CES1MAPTELANEALDH1A1 | |
| SCHEMBL9292108 | 0.82 | KCNN4 (0.48) | KCNN4SRCCES1TSHRMAPT | |
| SCHEMBL10335666 | 0.82 | KCNN4 (0.49) | KCNN4SRCCES1TSHRMAPT | |
| SCHEMBL10334822 | 0.82 | KCNN4 (0.49) | KCNN4SRCCES1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 898 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| EP-1771067-B1 | SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2014-03-12 | — | — | EP | claimed |
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | claimed |
| EP-1855529-B1 | SPIROKETAL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-12-18 | — | — | EP | claimed |
| EP-1966135-B1 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2013-10-09 | — | — | EP | claimed |
| EP-1206188-A1 | HERBICIDE/SAFENER COMBINATION PRODUCTS | Aventis CropScience GmbH (DE) | 2002-05-22 | — | — | EP | claimed |
| EP-1130965-A1 | COMBINATIONS OF HERBICIDES AND SAFENERS | Aventis CropScience GmbH (DE) | 2001-09-12 | — | — | EP | claimed |
| EP-1089627-A1 | COMBINATION OF HERBICIDES AND SAFENERS | Aventis CropScience GmbH (DE) | 2001-04-11 | — | — | EP | claimed |
| WO-2001008488-A1 | HERBICIDE/SAFENER COMBINATION PRODUCTS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-08 | — | — | WO | claimed |
| WO-2001008487-A1 | COMBINATIONS CONSISTING OF HERBICIDES AND SAFENERS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-08 | — | — | WO | claimed |
| WO-2000030447-A1 | COMBINATIONS OF HERBICIDES AND SAFENERS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-06-02 | — | — | WO | claimed |
| WO-2000011954-A1 | HERBICIDAL METHOD | AVENTIS CROPSCIENCE S.A. (FR) | 2000-03-09 | — | — | WO | claimed |
| WO-1999066795-A1 | COMBINATION OF HERBICIDES AND SAFENERS | AVENTIS CROPSCIENCE GMBH (DE) | 1999-12-29 | — | — | WO | claimed |
| US-5321000-A | Benzhydryl compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | claimed |
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | KCNN4 840/4885SRC 3283/4885CES1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.