Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 8/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.41 |
| ▸ | CDK1 | P06493 | 6/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 6/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426466 | 1.00 | MAPT (0.56) | MAPTTDP1LMNAHTTNCOA1 | |
| SCHEMBL3425190 | 0.86 | CDK5 (0.42) | MAPTTDP1LMNAHTTNCOA1 | |
| SCHEMBL3425188 | 0.86 | CDK5 (0.42) | MAPTTDP1LMNAHTTNCOA1 | |
| SCHEMBL3423063 | 0.84 | CDK5 (0.48) | MAPTLMNACDK5CDK5R1CCNB2 | |
| SCHEMBL3429343 | 0.84 | CDK5 (0.45) | MAPTLMNACDK5CDK5R1CCNB2 | |
| SCHEMBL3429340 | 0.84 | CDK5 (0.45) | MAPTLMNACDK5CDK5R1CCNB2 | |
| SCHEMBL3426079 | 0.84 | CDK5 (0.46) | MAPTLMNACDK5CDK5R1CCNB2 | |
| SCHEMBL3423058 | 0.84 | CDK5 (0.48) | MAPTLMNACDK5CDK5R1CCNB2 | |
| SCHEMBL3426076 | 0.84 | CDK5 (0.46) | MAPTLMNACDK5CDK5R1CCNB2 | |
| SCHEMBL3427595 | 0.83 | CDK5 (0.39) | MAPTTDP1LMNAHTTNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423031-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2008-09-09 | — | — | US | claimed |
| US-20050153955-A1 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2005-07-14 | — | — | US | claimed |
| WO-2004098520-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2004-11-18 | — | — | WO | claimed |
| US-7713958-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2010-05-11 | — | — | US | disclosed |
| US-20090137555-A1 | Compounds and Compositions as Protein Kinase Inhibitors | IRM LLC (BM) | 2009-05-28 | — | — | US | disclosed |
| US-7423031-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2008-09-09 | — | — | US | disclosed |
| WO-2004098520-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153955-A1 | Compounds and compositions as protein kinase inhibitors | CDK1, CDK3, CDK11A | MAPT 1666/4885TDP1 658/4885LMNA 1252/4885 |
| US-20090137555-A1 | Compounds and Compositions as Protein Kinase Inhibitors | CDK1, CDK3, CDK2 | MAPT 1424/4885TDP1 955/4885LMNA 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.