Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431629 | 0.77 | NR4A2 (0.46) | NR1H4TP53GAAGABRDGABRB1 | |
| SCHEMBL3430234 | 0.76 | NR1H4 (0.41) | NR1H4TP53GAAGABRDGABRB1 | |
| SCHEMBL3435404 | 0.72 | NR1H4 (0.36) | NR1H4TP53GAAGABRDGABRB1 | |
| SCHEMBL3435401 | 0.71 | NR1H4 (0.34) | NR1H4TP53GAAGABRDGABRB1 | |
| SCHEMBL219497 | 0.71 | NR1H4 (0.42) | NR1H4TP53GAAGABRDGABRB1 | |
| Hydrochloric Acid SCHEMBL6521449 | 0.71 | NR1H4 (0.52) | NR1H4TP53GAAGABRDGABRB1 | |
| SCHEMBL218008 | 0.70 | NR1H4 (0.43) | NR1H4TP53GAAGABRDGABRB1 | |
| SCHEMBL3429663 | 0.70 | NR1H4 (0.53) | NR1H4TP53GAAGABRDGABRB1 | |
| SCHEMBL220518 | 0.70 | NR1H4 (0.45) | NR1H4TP53GAAGABRDGABRB1 | |
| SCHEMBL3409535 | 0.69 | CYP11B1 (0.46) | NR1H4TP53GAAGABRDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262805-A1 | POLYSUBSTITUTED DERIVATIVES OF 2-HETEROARYL-6-PHENYL-IMIDAZO[L,2-A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009144395-A1 | POLYSUBSTITUTED DERIVATIVES OF 2-HETEROARYL-6-PHENYL-IMIDAZO[L,2- Α] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-12-03 | — | — | WO | disclosed |