Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10314493 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL1079829 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL10314231 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL3425434 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL4291973 | 0.86 | SMO (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1SMO | |
| Hydrochloric Acid SCHEMBL1055344 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL3428846 | 0.86 | SMO (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL1061755 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL10314464 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL1058147 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |