Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 12/20 | 0.81 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512004 | 1.00 | AVPR1A (0.81) | AVPR1ACNR1OXTRCNR2IL1B | |
| SCHEMBL2524189 | 0.91 | AVPR1A (0.68) | AVPR1ACNR1OXTRCNR2 | |
| SCHEMBL2524187 | 0.91 | AVPR1A (0.68) | AVPR1ACNR1OXTRCNR2 | |
| SCHEMBL4361697 | 0.90 | AVPR1A (1.00) | AVPR1ACNR1OXTRCNR2 | |
| SCHEMBL4357753 | 0.90 | AVPR1A (1.00) | AVPR1ACNR1OXTRCNR2 | |
| SCHEMBL2515628 | 0.88 | AVPR1A (0.64) | AVPR1ACNR1OXTRCNR2IL1B | |
| SCHEMBL3393027 | 0.86 | AVPR1A (0.81) | AVPR1ACNR1OXTRCNR2IL1B | |
| Hydrochloric Acid SCHEMBL2515633 | 0.85 | AVPR1A (0.80) | AVPR1ACNR1OXTRCNR2IL1B | |
| SCHEMBL2514280 | 0.85 | AVPR1A (0.79) | AVPR1ACNR1OXTRCNR2IL1B | |
| SCHEMBL2519890 | 0.85 | AVPR1A (0.79) | AVPR1ACNR1OXTRCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125827-B1 | AZASPIRO DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-11-03 | — | — | EP | claimed |