⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698115 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL3238307 | 0.77 | GAA (0.34) | — | |
| SCHEMBL9906470 | 0.76 | — | — | |
| SCHEMBL122205 | 0.74 | — | — | |
| SCHEMBL607414 | 0.74 | — | — | |
| SCHEMBL27466073 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL9656495 | 0.74 | TSHR (0.42) | — | |
| SCHEMBL10085240 | 0.74 | TSHR (0.36) | — | |
| SCHEMBL28140523 | 0.74 | — | — | |
| SCHEMBL4408191 | 0.72 | SLC22A6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46234-E1 | Tissue adhesive and sealant comprising polyglycerol aldehyde | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2016-12-13 | — | — | US | disclosed |
| US-8680200-B2 | Polyglycerol aldehydes | ACTAMAX SURGICAL MATERIALS LLC (US) | 2014-03-25 | — | — | US | disclosed |
| US-8404779-B2 | Tissue adhesive and sealant comprising polyglycerol aldehyde | ACTAMAX SURGICAL MATERIALS LLC (US) | 2013-03-26 | — | — | US | disclosed |
| EP-2411448-B1 | POLYGLYCEROL ALDEHYDES | ACTAMAX SURGICAL MATERIALS LLC (US) | 2013-03-20 | — | — | EP | disclosed |
| CN-102365101-A | Tissue adhesives and sealants comprising polyglycerol aldehydes | DU PONT | 2012-02-29 | — | — | CN | disclosed |
| CN-102361911-A | Polyglycerol aldehydes | DU PONT | 2012-02-22 | — | — | CN | disclosed |
| US-20120029149-A1 | POLYGLYCEROL ALDEHYDES | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-02-02 | — | — | US | disclosed |
| EP-2411448-A1 | POLYGLYCEROL ALDEHYDES | Actamax Surgical Materials LLC (US) | 2012-02-01 | — | — | EP | disclosed |
| EP-2411062-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | Actamax Surgical Materials LLC (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20120014909-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-01-19 | — | — | US | disclosed |
| WO-2010111570-A1 | POLYGLYCEROL ALDEHYDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111594-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-30 | — | — | WO | disclosed |