Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062478 | 0.93 | SMO (0.83) | SMONPSR1SSTR5 | |
| SCHEMBL13708860 | 0.91 | SMO (0.67) | SMOSSTR5 | |
| SCHEMBL1056681 | 0.91 | SMO (0.69) | SMO | |
| SCHEMBL10314248 | 0.90 | SMO (0.64) | SMO | |
| Hydrochloric Acid SCHEMBL1060009 | 0.89 | SMO (0.63) | SMO | |
| SCHEMBL1060514 | 0.87 | SMO (0.85) | SMONPSR1 | |
| SCHEMBL1062087 | 0.86 | SMO (0.81) | SMONPSR1KMT2A | |
| SCHEMBL1081991 | 0.86 | SMO (0.83) | SMONPSR1KMT2A | |
| SCHEMBL1083651 | 0.86 | SMO (0.83) | SMONPSR1KMT2A | |
| SCHEMBL1063022 | 0.85 | SMO (0.68) | SMOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |