Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428846 | 0.91 | SMO (0.43) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10314458 | 0.90 | SMO (0.42) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4288547 | 0.90 | SMO (0.43) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1058141 | 0.89 | SMO (0.41) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17677387 | 0.87 | SMO (0.41) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1063825 | 0.87 | SMO (0.44) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1057466 | 0.86 | SMO (0.42) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1063813 | 0.85 | SMO (0.40) | SMOALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10314457 | 0.85 | SMO (0.41) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10314230 | 0.85 | SMO (0.45) | SMOALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |