Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365373 | 1.00 | AR (0.34) | ARPGRNPSR1NPC1RAB9A | |
| SCHEMBL1365211 | 1.00 | AR (0.34) | ARPGRNPSR1NPC1RAB9A | |
| SCHEMBL1364558 | 0.91 | AR (0.36) | ARPGRCXCR1CXCR2ALDH1A1 | |
| SCHEMBL1363601 | 0.91 | AR (0.36) | ARPGRCXCR1CXCR2ALDH1A1 | |
| SCHEMBL1364858 | 0.90 | AR (0.37) | ARPGRCXCR1CXCR2 | |
| SCHEMBL1363281 | 0.90 | AR (0.37) | ARPGRCXCR1CXCR2 | |
| SCHEMBL3411479 | 0.90 | AR (0.37) | ARPGRCXCR1CXCR2 | |
| SCHEMBL1365840 | 0.88 | AR (0.34) | ARPGRS1PR3 | |
| SCHEMBL1363120 | 0.88 | AR (0.34) | ARPGRS1PR3 | |
| SCHEMBL3408782 | 0.88 | S1PR3 (0.38) | ARPGRS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260028-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | Radius Health, Inc. (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009105214-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2009-08-27 | — | — | WO | disclosed |