Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.72 |
| ▸ | PLAU | P00749 | 5/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6113809 | 0.77 | ELANE (0.69) | ELANEPLAUF2 | |
| SCHEMBL5989502 | 0.77 | ELANE (0.73) | ELANEPLAUF2 | |
| SCHEMBL27732402 | 0.75 | ELANE (0.60) | ELANEPLAUF2RORC | |
| SCHEMBL3428237 | 0.73 | ELANE (0.71) | ELANE | |
| SCHEMBL260569 | 0.70 | KDM4E (0.60) | ELANE | |
| SCHEMBL29789796 | 0.70 | KDM4E (0.60) | ELANE | |
| SCHEMBL27732380 | 0.70 | ELANE (0.72) | ELANEPLAUF2RORC | |
| SCHEMBL27712246 | 0.70 | ELANE (0.62) | ELANEPLAUF2RORC | |
| SCHEMBL27712237 | 0.69 | ELANE (0.75) | ELANEPLAUF2 | |
| SCHEMBL28770695 | 0.69 | ELANE (0.65) | ELANEPLAUF2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257340-A2 | COMPOUNDS FOR TREATING MUSCULAR DYSTROPHY | BioMarin IGA Limited (BS) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009121623-A2 | COMPOUNDS FOR TREATING MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-10-08 | — | — | WO | disclosed |