Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791951 | 0.97 | TSHR (0.46) | CES2CES1TSHRFAAHGPR84 | |
| SCHEMBL161332 | 0.92 | — | — | |
| SCHEMBL797999 | 0.78 | TSHR (0.46) | CES2CES1TSHRFAAHAKR1B1 | |
| SCHEMBL11125330 | 0.76 | TSHR (0.46) | CES2CES1TSHRFAAHGPR84 | |
| SCHEMBL142676 | 0.76 | — | — | |
| SCHEMBL16030163 | 0.76 | TSHR (0.46) | CES2CES1TSHRFAAHGPR84 | |
| SCHEMBL3037978 | 0.76 | — | — | |
| SCHEMBL1533739 | 0.76 | TSHR (0.43) | CES2CES1TSHRFAAHAKR1B1 | |
| SCHEMBL4228159 | 0.76 | — | — | |
| SCHEMBL8706420 | 0.76 | TSHR (0.42) | CES2CES1TSHRFAAHAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5303081-B2 | — | — | 2013-10-02 | — | — | JP | disclosed |
| JP-2010092706-A | POSITIVE ELECTRODE MATERIAL FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | UNIV OF FUKUI | 2010-04-22 | — | — | JP | disclosed |
| US-6656384-B1 | Polymerized liquid crystalline filaments formed when a liquid crystalline solution undergoes a phase transition from the isotropic phase to the smectic phase; 4-(1-Octenyloxy)-4-cyanobiphenyl (OOCB) is the preferred liquid crystal monomer | KENT STATE UNIVERSITY | 2003-12-02 | — | — | US | disclosed |
| US-4194920-A | EMULSION POLYMERIZATION TO ENCAPSULATE MICRONIZED PIGMENTS | Darrah, Marion (US) | 1980-03-25 | — | — | US | disclosed |
| US-4154621-A | Intrachromoleucospheruloid pigment compositions and processes for producing the same | Darrah, Marion (US) | 1979-05-15 | — | — | US | disclosed |