Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | SDHA | P31040 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CALML3 | P27482 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208267 | 1.00 | CHRM1 (0.44) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL3208273 | 1.00 | CHRM1 (0.44) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL3209762 | 0.95 | CHRM1 (0.49) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL3209760 | 0.95 | CHRM1 (0.49) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL15642954 | 0.90 | CALML3 (0.48) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL13484640 | 0.90 | CALML3 (0.48) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL3196643 | 0.89 | CHRM1 (0.52) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL3193980 | 0.89 | CHRM1 (0.52) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL3206370 | 0.88 | CHRM1 (0.45) | CHRM1MAOAMAOBPTGS1SDHA | |
| SCHEMBL3206365 | 0.88 | CHRM1 (0.45) | CHRM1MAOAMAOBPTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254892-A1 | BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES | Global Alliance For Tb Drug Development (US) | 2010-12-01 | — | — | EP | claimed |
| WO-2009120789-A1 | BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2009-10-01 | — | — | WO | claimed |