⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15284357 | 0.97 | — | — | |
| SCHEMBL15284451 | 0.97 | — | — | |
| SCHEMBL15284394 | 0.97 | — | — | |
| SCHEMBL23856 | 0.89 | — | — | |
| SCHEMBL15994775 | 0.67 | — | — | |
| SCHEMBL15283847 | 0.67 | — | — | |
| SCHEMBL15283824 | 0.65 | — | — | |
| SCHEMBL15284597 | 0.65 | — | — | |
| SCHEMBL15994767 | 0.65 | — | — | |
| SCHEMBL143260 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 44100 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362369-B1 | — | — | None | — | — | US | claimed |
| WO-2024149340-A1 | INDOLONE DERIVATIVE HAVING IRAK4 INHIBITORY ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳众格生物科技有限公司 | 2024-07-18 | — | — | WO | claimed |
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | claimed |
| EP-4399204-A1 | POTENT AND SELECTIVE INHIBITORS OF IRAK4 | Dana-Farber Cancer Institute, Inc. (US) | 2024-07-17 | — | — | EP | claimed |
| US-20240228468-A1 | N-(6-((OCTAHYDROCYCLOPENTA[C]PYRROL-5-YI)AMINO)PYRIDAZIN-3-YL)PHENYL)CARBOXAMIDE AND (6- ((OCTAHYDROCYCLOPENTA[C]PYRROL-5-YL)AMINO)PYRIDAZIN-3-YL)BENZAMIDE DERIVATIVES AS MACHR M4 ANTAGONISTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | VANDERBILT UNIVERSITY | 2024-07-11 | — | — | US | claimed |
| WO-2024146627-A1 | MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 | 北京清辉联诺生物科技有限责任公司 | 2024-07-11 | — | — | WO | claimed |
| CN-113493441-B | Novel spiro compound and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118290322-A | Aromatic molecules for the treatment of pathological conditions | 赛尼欧普罗有限责任公司 | 2024-07-05 | — | — | CN | claimed |
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-07-04 | — | — | US | claimed |
| WO-2024140638-A1 | COMPOUND BASED ON SULFUR/OXYGEN SUBSTITUTED GLUTARIMIDE-BASED ISOINDOLINONE SKELETON AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-07-04 | — | — | WO | claimed |
| US-4558038-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORP. (US) | 1985-12-10 | — | — | US | claimed |
| US-4529796-A | Method for making chromogenic and/or fluorogenic substrates for use in monitoring catalytic or enzymatic activity | BAKER INSTRUMENTS CORPORATION (US) | 1985-07-16 | — | — | US | claimed |
| EP-0136702-A2 | Cyclohexenol derivatives, process for their preparation and their use in combating undesirable plant growth | BASF Aktiengesellschaft (DE) | 1985-04-10 | — | — | EP | claimed |
| US-4479966-A | 6,9-Methano-PGI2 analogues | ONO PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-10-30 | — | — | US | claimed |
| US-4422864-A | Cyclohexanedione derivatives, their preparation and herbicides containing them | BASF AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | claimed |
| US-4362875-A | Process for preparing (1-acylaminomethyl)-1,2,3,4-tetrahydroisoquinolines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-12-07 | — | — | US | claimed |
| EP-0061760-A1 | A method for preparing a mononucleotide-3'-phosphodiester-based substrate | Baker Instruments Corporation (US) | 1982-10-06 | — | — | EP | claimed |
| US-4334010-A | Silver halide photographic light-sensitive element | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-08 | — | — | US | claimed |
| US-4199588-A | TRANQUILIZERS, MUSCLE RELAXANTS, ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-04-22 | — | — | US | claimed |
| US-4160098-A | DIURETICS, SALURETICS, HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-03 | — | — | US | claimed |