Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 10/20 | 1.00 |
| ▸ | LOX | P28300 | 2/20 | 0.56 |
| ▸ | AOC1 | P19801 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624877 | 0.77 | AOC3 (0.63) | AOC3LOXCA12CA1CA2 | |
| SCHEMBL5009758 | 0.77 | AOC3 (0.63) | AOC3LOXAOC1CA12CA1 | |
| Hydrochloric Acid SCHEMBL5012116 | 0.76 | AOC3 (0.64) | AOC3LOXAOC1ALDH1A1DPP4 | |
| SCHEMBL3934756 | 0.76 | AOC3 (0.61) | AOC3ALDH1A1HPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL10352250 | 0.74 | AOC3 (0.62) | AOC3ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL17372010 | 0.72 | AOC3 (0.56) | AOC3AOC1CA12CA1CA2 | |
| SCHEMBL25384122 | 0.71 | AOC3 (0.55) | AOC3CA12CA1CA2CA9 | |
| SCHEMBL11092365 | 0.70 | AOC3 (0.53) | AOC3CA12CA1CA2CA9 | |
| SCHEMBL25384084 | 0.68 | AOC3 (0.52) | AOC3LOXCA12CA1CA2 | |
| SCHEMBL31274793 | 0.68 | AOC3 (0.52) | AOC3LOXCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906642-B2 | Methods and compositions for the treatment and diagnosis of haemorrhagic conversion | UNIVERSITAT AUTONOMA DE BARCELONA (ES) | 2014-12-09 | — | — | US | disclosed |
| US-8636995-B2 | Methods and devices to regulate stem cell homing | CARDIAC PACEMAKERS, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-20120014939-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF HAEMORRHAGIC CONVERSION | UNIVERSITAT AUTONOMA DE BARCELONA (ES) | 2012-01-19 | — | — | US | disclosed |
| EP-2357252-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF HAEMORRHAGIC CONVERSION | Universitat Autònoma De Barcelona (ES) | 2011-08-17 | — | — | EP | disclosed |
| US-20080057027-A1 | METHODS AND DEVICES TO REGULATE STEM CELL HOMING | CARDIAC PACEMAKERS, INC (US) | 2008-03-06 | — | — | US | disclosed |
| US-20080058922-A1 | METHODS AND DEVICES EMPLOYING VAP-1 INHIBITORS | CARDIAC PACEMAKERS, INC. (US) | 2008-03-06 | — | — | US | disclosed |