Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414719 | 0.87 | MEN1 (0.70) | MEN1KMT2ARAB9ANPC1CYP2D6 | |
| SCHEMBL30046349 | 0.85 | SCN9A (0.76) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL28038743 | 0.82 | CDK5 (0.58) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL691596 | 0.82 | MEN1 (0.67) | MEN1KMT2ARAB9ANPC1CYP2D6 | |
| SCHEMBL690592 | 0.81 | EGFR (0.55) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL13064955 | 0.81 | CDK5 (0.61) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL374096 | 0.81 | CDK5 (0.61) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL374472 | 0.80 | EGFR (0.64) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL8798667 | 0.80 | EGFR (0.61) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL857502 | 0.78 | NPC1 (0.63) | CDK2MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073361-B | Rosin diterpenoid compound and preparation method and application thereof | 广东药科大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-115073361-A | Rosin diterpenoid compound and preparation method and application thereof | 广东药科大学 | 2022-09-20 | — | — | CN | disclosed |
| US-20100172970-A1 | ANTIVIRAL COMPOSITIONS | VERRECK GEERT | 2010-07-08 | — | — | US | disclosed |
| US-20070196478-A1 | ANTIVIRAL COMPOSITIONS | VERRECK GEERT | 2007-08-23 | — | — | US | disclosed |
| US-7241458-B1 | Antiviral compositions | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |
| EP-1225874-B1 | ANTIVIRAL SOLID DISPERSIONS | JANSSEN PHARMACEUTICA NV (BE) | 2006-02-01 | — | — | EP | disclosed |
| CN-1234347-C | Anti-virus composition | JANSSEN PHARMACEUTICA NV (BE) | 2006-01-04 | — | — | CN | disclosed |
| CN-1376057-A | Anti-virus composition | JANSSEN PHARMACEUTICA NV (BE) | 2002-10-23 | — | — | CN | disclosed |
| EP-1225874-A1 | ANTIVIRAL COMPOSITIONS | Janssen Pharmaceutica N.V. (BE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001022938-A1 | ANTIVIRAL COMPOSITIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196478-A1 | ANTIVIRAL COMPOSITIONS | EIF2AK2, ZC3HAV1, RPL35 | CDK1 1528/4885CCNB1 2521/4885CCNA2 2546/4885 |
| US-20100172970-A1 | ANTIVIRAL COMPOSITIONS | EIF2AK2, ZC3HAV1, RPL35 | CDK1 1528/4885CCNB1 2521/4885CCNA2 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.