Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2082965 | 0.93 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL3432217 | 0.88 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL2084155 | 0.88 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL2084711 | 0.85 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL2083633 | 0.82 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL2084142 | 0.78 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL12936360 | 0.76 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL2085151 | 0.76 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL2082824 | 0.75 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DCA2 | |
| SCHEMBL2082733 | 0.75 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245017-A2 | NOVEL HETEROCYCLES | Orchid Research Laboratories Limited (IN) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009095773-A2 | NOVEL HETEROCYCLES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-08-06 | — | — | WO | disclosed |