Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183755 | 0.79 | HSP90AA1 (0.40) | HSP90AA1MTOR | |
| SCHEMBL27851808 | 0.72 | HSP90AA1 (0.54) | HSP90AA1 | |
| SCHEMBL2183955 | 0.72 | HSP90AA1 (0.47) | HSP90AA1 | |
| SCHEMBL13658316 | 0.72 | HSP90AA1 (0.58) | HSP90AA1 | |
| SCHEMBL28794448 | 0.71 | HSP90AA1 (0.48) | HSP90AA1 | |
| SCHEMBL3432987 | 0.71 | HSP90AA1 (0.64) | HSP90AA1 | |
| SCHEMBL2185438 | 0.71 | HSP90AA1 (0.54) | HSP90AA1 | |
| SCHEMBL2185440 | 0.71 | HSP90AA1 (0.54) | HSP90AA1 | |
| Hydrochloric Acid SCHEMBL2183417 | 0.71 | HSP90AA1 (0.63) | HSP90AA1 | |
| SCHEMBL2183963 | 0.70 | HSP90AA1 (0.51) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265598-A2 | NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | Sanofi-Aventis (FR) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009122034-A2 | NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-10-08 | — | — | WO | disclosed |