⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16963894 | 0.75 | — | — | |
| SCHEMBL885484 | 0.73 | — | — | |
| SCHEMBL16963900 | 0.65 | — | — | |
| SCHEMBL4501720 | 0.65 | — | — | |
| SCHEMBL1851536 | 0.63 | — | — | |
| SCHEMBL885539 | 0.63 | HCAR2 (0.41) | — | |
| SCHEMBL5137289 | 0.60 | — | — | |
| SCHEMBL4837708 | 0.59 | — | — | |
| SCHEMBL10157463 | 0.56 | — | — | |
| SCHEMBL5279992 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893871-B1 | BENZIMIDAZOLONE DERIVATIVES, AND ANALOGUES THEREOF, AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2024-04-10 | — | — | EP | disclosed |
| US-11458124-B2 | Spirocyclic indane analogues as IL-17 modulators | UCBBiopharma Srl (BE) | 2022-10-04 | — | — | US | disclosed |
| US-20210380573-A1 | Benzimidazolone Derivatives, and Analogues Thereof, as IL-17 Modulators | UCB BIOPHARMA SRL (SOCIETE A RESPONSABILITE LIMITEE) (BE) | 2021-12-09 | — | — | US | disclosed |
| EP-3894003-A1 | FUNCTIONALISED AMINE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3893871-A1 | BENZIMIDAZOLONE DERIVATIVES, AND ANALOGUES THEREOF, AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2021-10-20 | — | — | EP | disclosed |
| US-20210228547-A1 | Spirocyclic Indane Analogues as IL-17 Modulators | UCB BIOPHARMA SRL (SOCIETE A RESPONSABILITE LIMITEE) (BE) | 2021-07-29 | — | — | US | disclosed |
| US-11052076-B2 | Spirocyclic indolines as IL-17 modulators | UCB Biopharma SRL (BE) | 2021-07-06 | — | — | US | disclosed |
| EP-3820567-A1 | SPIROCYCLIC INDANE ANALOGUES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2021-05-19 | — | — | EP | disclosed |
| WO-2020120141-A1 | FUNCTIONALISED AMINE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020120140-A1 | BENZIMIDAZOLONE DERIVATIVES, AND ANALOGUES THEREOF, AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-06-18 | — | — | WO | disclosed |
| US-20200138797-A1 | Spirocyclic Indolines as IL-17 Modulators | UCB Biopharma SRL (BE) | 2020-05-07 | — | — | US | disclosed |
| EP-3638227-A1 | SPIROCYCLIC INDOLINES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-04-22 | — | — | EP | disclosed |
| WO-2020011731-A1 | SPIROCYCLIC INDANE ANALOGUES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-01-16 | — | — | WO | disclosed |
| WO-2018229079-A1 | SPIROCYCLIC INDOLINES AS IL-17 MODULATORS | UCB BIOPHARMA SPRL (BE) | 2018-12-20 | — | — | WO | disclosed |
| WO-2010146351-A1 | INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-12-23 | — | — | WO | disclosed |
| US-20090076075-A1 | QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | disclosed |