Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187532 | 0.98 | KDM4E (0.97) | KDM4ELMNATDP1CA1CA2 | |
| SCHEMBL2593142 | 0.98 | KDM4E (0.97) | KDM4ELMNATDP1CA1CA2 | |
| SCHEMBL2593144 | 0.98 | KDM4E (0.97) | KDM4ELMNATDP1CA1CA2 | |
| SCHEMBL5717320 | 0.86 | KDM4E (0.75) | KDM4ELMNATDP1CA1CA2 | |
| SCHEMBL5717324 | 0.86 | KDM4E (0.75) | KDM4ELMNATDP1CA1CA2 | |
| SCHEMBL16178828 | 0.83 | KDM4E (0.71) | KDM4ELMNATDP1CA1CA2 | |
| SCHEMBL5717407 | 0.78 | — | — | |
| SCHEMBL7180702 | 0.68 | KDM4E (0.51) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5961659 | 0.68 | KDM4E (0.51) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5961657 | 0.68 | KDM4E (0.51) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002568-A1 | AZAINDOLE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
| WO-2010122979-A1 | THIAZOLIDINONE DERIVATIVE | ＳＢＩバイオテック株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |