⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361565 | 0.72 | — | — | |
| SCHEMBL3671706 | 0.70 | — | — | |
| SCHEMBL9838352 | 0.69 | — | — | |
| SCHEMBL3666532 | 0.67 | — | — | |
| SCHEMBL9318653 | 0.67 | — | — | |
| SCHEMBL8518166 | 0.67 | — | — | |
| SCHEMBL1472599 | 0.67 | — | — | |
| SCHEMBL3804318 | 0.65 | — | — | |
| SCHEMBL9603578 | 0.65 | — | — | |
| SCHEMBL18918479 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273696-A1 | Composition and method for the prevention and removal of unwanted paint on a surface | HOPFSTOCK HERBERT | 2010-10-28 | — | — | US | claimed |
| US-20100273696-A1 | Composition and method for the prevention and removal of unwanted paint on a surface | HOPFSTOCK HERBERT | 2010-10-28 | — | — | US | disclosed |
| US-20100273696-A1 | Composition and method for the prevention and removal of unwanted paint on a surface | HOPFSTOCK HERBERT | 2010-10-28 | — | — | US | disclosed |
| US-7087776-B2 | Silanol enzyme inhibitors | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2006-08-08 | — | — | US | disclosed |
| US-6960678-B2 | Silanol enzyme inhibitors | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2005-11-01 | — | — | US | disclosed |
| EP-1019533-B1 | SILANOL ENZYME INHIBITORS | UNIV NEW YORK STATE RES FOUND (US) | 2005-09-21 | — | — | EP | disclosed |
| US-20050171059-A1 | Silanol enzyme inhibitors | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK. | 2005-08-04 | — | — | US | disclosed |
| US-20030096793-A1 | Inhibit protease enzymes; Benzyl 5-(benzoylamino)-4,4-dihydroxy-7- methyl-4-sila-octanamide, for example can be used to inhibit HIV protease in the treatment of AIDS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2003-05-22 | — | — | US | disclosed |
| US-6441212-B1 | SILANEDIOL TRIMER OR LARGER MOIETY CONTAINING AT LEAST ONE AMINO OR AMIDO GROUP; ISOSTERES THAT ASPARTIC PROTEASES ACT UPON; NOT CLEAVED UNDER ENZYMATIC CONDITIONS; HUMAN IMMUNODEFICIENCY VIRUS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-08-27 | — | — | US | disclosed |
| EP-1019533-A4 | SILANOL ENZYME INHIBITORS | UNIV NEW YORK STATE RES FOUND (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-1019533-A1 | SILANOL ENZYME INHIBITORS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-07-19 | — | — | EP | disclosed |
| US-5760019-A | INHIBIT PROTEASE ENZYMES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0558047-B1 | Copolymer having amino group and process for production thereof | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1998002578-A1 | SILANOL ENZYME INHIBITORS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-01-22 | — | — | WO | disclosed |
| US-5486581-A | IODIDE SALTS | SHELL OIL COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0558047-A2 | Copolymer having amino group and process for production thereof | DAI-ICHI KOGYO SEIYAKU Co., Ltd. (JP) | 1993-09-01 | — | — | EP | disclosed |