Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 12/20 | 0.50 |
| ▸ | BTK | Q06187 | 5/20 | 0.48 |
| ▸ | ITK | Q08881 | 3/20 | 0.48 |
| ▸ | BMX | P51813 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774201 | 1.00 | KMT2A (0.61) | KMT2AEGFRBTKITKBMX | |
| SCHEMBL14675141 | 1.00 | KMT2A (0.61) | KMT2AEGFRBTKITKBMX | |
| SCHEMBL3434611 | 0.93 | KMT2A (0.56) | KMT2AEGFRBTKITKBMX | |
| SCHEMBL28333053 | 0.93 | KMT2A (0.56) | KMT2AEGFRBTKITKBMX | |
| SCHEMBL17797488 | 0.88 | EGFR (0.65) | KMT2AEGFRBTKITKBMX | |
| SCHEMBL17797487 | 0.88 | EGFR (0.65) | KMT2AEGFRBTKITKBMX | |
| SCHEMBL14674931 | 0.86 | JAK3 (0.56) | KMT2AEGFRITKJAK3 | |
| SCHEMBL1694067 | 0.86 | JAK3 (0.44) | KMT2AEGFRBTKITKJAK3 | |
| SCHEMBL17797630 | 0.85 | MAPK3 (0.53) | KMT2AEGFRBTKITKJAK3 | |
| SCHEMBL2128326 | 0.84 | KMT2A (0.53) | KMT2AEGFRBTKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12357631-B2 | Pyrrolo[2,3-B]pyridin derivatives as inhibitors of influenza virus replication | COCRYSTAL PHARMA, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| EP-3829719-B1 | PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION | COCRYSTAL PHARMA INC (US) | 2025-04-02 | — | — | EP | disclosed |
| CN-112638477-B | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-3427738-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-3829719-A1 | PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION | Cocrystal Pharma, Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| US-20210121462-A1 | PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2021-04-29 | — | — | US | disclosed |
| CN-112638477-A | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2021-04-09 | — | — | CN | disclosed |
| US-10874673-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-12-29 | — | — | US | disclosed |
| WO-2020023813-A1 | PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION | COCRYSTAL PHARMA, INC. (US) | 2020-01-30 | — | — | WO | disclosed |
| CN-104922128-B | Inhibitors of influenza virus replication | 沃泰克斯药物股份有限公司 | 2019-12-20 | — | — | CN | disclosed |
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9518056-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2442809-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2016-08-31 | — | — | EP | disclosed |
| US-20160152614-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2016-06-02 | — | — | US | disclosed |
| US-9345708-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-05-24 | — | — | US | disclosed |
| US-20140296201-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2014-10-02 | — | — | US | disclosed |
| US-8829007-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-09-09 | — | — | US | disclosed |
| US-20140142119-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-05-22 | — | — | US | disclosed |
| US-20120171245-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-07-05 | — | — | US | disclosed |
| WO-2010148197-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296201-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | KMT2A 1893/4885EGFR 688/4885BTK 533/4885 |
| US-10874673-B2 | Inhibitors of influenza viruses replication | ACE, IRF3, ACE2 | KMT2A 1893/4885EGFR 688/4885BTK 533/4885 |
| US-20120171245-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | KMT2A 1893/4885EGFR 688/4885BTK 533/4885 |
| US-20210121462-A1 | PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION | PIR, PNPO, IDO1 | KMT2A 2767/4885EGFR 2292/4885BTK 2667/4885 |
| US-20160152614-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | KMT2A 1893/4885EGFR 688/4885BTK 533/4885 |
| US-12357631-B2 | Pyrrolo[2,3-B]pyridin derivatives as inhibitors of influenza virus replication | PIR, PNPO, IDO1 | KMT2A 2767/4885EGFR 2292/4885BTK 2667/4885 |
| US-20140142119-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | KMT2A 1893/4885EGFR 688/4885BTK 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.