Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16739181 | 0.87 | PTPN1 (0.51) | AGTR2PTPN1 | |
| SCHEMBL1151768 | 0.80 | PTPN1 (0.40) | AGTR2CYP19A1PTPN1ELANEMAPT | |
| SCHEMBL23315195 | 0.70 | PTPN1 (0.55) | PTPN1 | |
| SCHEMBL1151342 | 0.69 | ACE (0.38) | AGTR2MAPT | |
| SCHEMBL21881597 | 0.69 | PTPN1 (0.54) | PTPN1 | |
| SCHEMBL1152110 | 0.69 | PTPN1 (0.42) | AGTR2CYP19A1PTPN1ELANE | |
| SCHEMBL539738 | 0.67 | PTPN1 (0.54) | PTPN1 | |
| SCHEMBL12849136 | 0.67 | PTPN1 (0.54) | PTPN1 | |
| SCHEMBL540106 | 0.66 | PTPN1 (0.51) | AGTR2PTPN1MAPT | |
| SCHEMBL6392086 | 0.65 | PTPN1 (0.63) | AGTR2PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262364-A2 | OXADIAZOANTHRACENE COMPOUNDS FOR THE TREATMENT OF DIABETES | TransTech Pharma, Inc (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009111700-A2 | OXADIAZOANTHRACENE COMPOUNDS FOR THE TREATMENT OF DIABETES | TRANSTECH PHARMA, INC. (US) | 2009-09-11 | — | — | WO | disclosed |