Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183561 | 1.00 | HSP90AA1 (0.39) | HSP90AA1LRRK2 | |
| SCHEMBL3435772 | 0.85 | HSP90AA1 (0.52) | HSP90AA1 | |
| SCHEMBL2185301 | 0.85 | HSP90AA1 (0.52) | HSP90AA1 | |
| SCHEMBL2183119 | 0.80 | BIRC5 (0.37) | HSP90AA1LRRK2 | |
| SCHEMBL2181737 | 0.80 | CYP11B1 (0.42) | HSP90AA1LRRK2 | |
| SCHEMBL2182330 | 0.79 | HSP90AA1 (0.40) | HSP90AA1 | |
| SCHEMBL2185438 | 0.79 | HSP90AA1 (0.54) | HSP90AA1 | |
| SCHEMBL2185440 | 0.79 | HSP90AA1 (0.54) | HSP90AA1 | |
| SCHEMBL2183243 | 0.79 | HSP90AA1 (0.55) | HSP90AA1 | |
| SCHEMBL2182392 | 0.78 | HSP90AA1 (0.46) | HSP90AA1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265598-A2 | NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | Sanofi-Aventis (FR) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009122034-A2 | NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-10-08 | — | — | WO | disclosed |