Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398354 | 0.91 | MEN1 (0.64) | MEN1KMT2ATP53PDE1CGAA | |
| SCHEMBL3393538 | 0.90 | MEN1 (0.78) | MEN1KMT2ATP53PDE1CGAA | |
| SCHEMBL3393219 | 0.90 | MEN1 (0.62) | MEN1KMT2ATP53PDE1CGAA | |
| SCHEMBL3394396 | 0.90 | MEN1 (0.58) | MEN1KMT2ATP53PDE1CNPSR1 | |
| SCHEMBL3399280 | 0.89 | MEN1 (0.61) | MEN1KMT2ATP53PDE1CGAA | |
| Hydrochloric Acid SCHEMBL3394808 | 0.89 | MEN1 (0.61) | MEN1KMT2ATP53PDE1CGAA | |
| SCHEMBL13426120 | 0.89 | PDE1C (0.59) | MEN1KMT2ATP53PDE1CNPSR1 | |
| SCHEMBL3395613 | 0.89 | MEN1 (0.60) | MEN1KMT2ATP53PDE1CGAA | |
| SCHEMBL13425692 | 0.89 | MEN1 (0.60) | MEN1KMT2ATP53PDE1CNPSR1 | |
| SCHEMBL3394404 | 0.89 | HSD17B10 (0.62) | MEN1KMT2ATP53PDE1CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |