Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Warfarin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 known ✓ | Q9BQB6 | 3/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.97 |
| ▸ | ALB | P02768 | 2/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.97 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.97 |
| ▸ | MEN1 | O00255 | 1/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.97 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.75 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | BRD4 | O60885 | 1/20 | 0.67 |
| ▸ | NQO1 | P15559 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Warfarin SCHEMBL28534047 | 1.00 | CYP2C9 (0.97) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL5483689 | 1.00 | CYP2C9 (0.97) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL8332637 | 1.00 | CYP2C9 (0.97) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL13278154 | 1.00 | CYP2C9 (0.97) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL29400364 | 0.99 | CYP2C9 (1.00) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL3689 | 0.99 | CYP2C9 (1.00) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL662875 | 0.99 | CYP2C9 (1.00) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL4439794 | 0.99 | CYP2C9 (1.00) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL2139452 | 0.99 | CYP2C9 (1.00) | CYP2C9VKORC1ALBHSD17B10KDM4E | |
| Warfarin SCHEMBL3792087 | 0.99 | CYP2C9 (1.00) | CYP2C9VKORC1ALBHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6738 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026087732-A1 | LIQUID, MULTI-DOSE, READY-TO-USE WARFARIN COMPOSITION AND USE | HYLORIS DEVELOPMENTS SA (BE) | 2026-04-30 | — | — | WO | claimed |
| EP-4688415-A1 | DOUBLE LAYER TUBING FOR IV INFUSION SETS | CareFusion 303, Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| CN-120005821-A | Immune cell culture method | 上海华颜医药科技有限公司 | 2025-05-16 | — | — | CN | claimed |
| WO-2025022245-A1 | A READY-TO-USE ORAL LIQUID FORMULATION OF WARFARIN SODIUM | LIQMEDS WORLDWIDE LIMITED (GB) | 2025-01-30 | — | — | WO | claimed |
| US-20240374769-A1 | LIGHT ACTIVATED CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2024-11-14 | — | — | US | claimed |
| WO-2024233595-A1 | LIGHT ACTIVATED CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2024-11-14 | — | — | WO | claimed |
| CN-118924473-A | Gingival bleeding animal model, method and application of chronic periodontitis with coagulation disorder | 上海交通大学医学院附属第九人民医院 | 2024-11-12 | — | — | CN | claimed |
| CN-118834562-A | Poria cocos acidic polysaccharide chiral stationary phase and application thereof | 云南中医药大学 | 2024-10-25 | — | — | CN | claimed |
| US-20240325623-A1 | DOUBLE LAYER TUBING FOR IV INFUSION SETS | CAREFUSION 303, INC. | 2024-10-03 | — | — | US | claimed |
| WO-2024205867-A1 | DOUBLE LAYER TUBING FOR IV INFUSION SETS | CAREFUSION 303, INC. (US) | 2024-10-03 | — | — | WO | claimed |
| WO-2001028555-A1 | EMULSION COMPOSITIONS FOR POLYFUNCTIONAL ACTIVE INGREDIENTS | LIPOCINE, INC. (US) | 2001-04-26 | — | — | WO | claimed |
| EP-1089992-A1 | SYNTHESES BASED ON 2-HYDROXYACETOPHENONE | Hoechst Celanese Corporation (US) | 2001-04-11 | — | — | EP | claimed |
| EP-1089992-A4 | SYNTHESES BASED ON 2-HYDROXYACETOPHENONE | HOECHST CELANESE CORP (US) | 2001-04-11 | — | — | EP | claimed |
| WO-2001012155-A1 | COMPOSITIONS AND METHODS FOR ENHANCED ABSORPTION OF HYDROPHILIC THERAPEUTIC AGENTS | LIPOCINE, INC. (US) | 2001-02-22 | — | — | WO | claimed |
| WO-2000024386-A1 | METHOD OF MAKING PRESSURE SENSITIVE ADHESIVE MATRIX PATCHES CONTAINING HYDROPHILIC SALTS OF DRUGS | THERATECH, INC. (US) | 2000-05-04 | — | — | WO | claimed |
| US-5935802-A | Method of assaying a blood sample for prothrombin | EVANSTON NORTHWESTERN HEALTHCARE RESEARCH INSTITUTE (US) | 1999-08-10 | — | — | US | claimed |
| CN-1194781-A | Method for obtainment of biological rodenticide | BIOLOG FARMACEUTICOS LABIOFAM (CU) | 1998-10-07 | — | — | CN | claimed |
| US-5696274-A | Syntheses based on 2-hydroxyacetophenone | HOECHST CELANESE CORPORATION (US) | 1997-12-09 | — | — | US | claimed |
| WO-1997024347-A1 | SYNTHESES BASED ON 2-HYDROXYACETOPHENONE | HOECHST CORPORATION (US) | 1997-07-10 | — | — | WO | claimed |
| US-5328453-A | Method for enhancing transdermal drug delivery of electrical drug applicators | DRUG DELIVERY SYSTEMS INC. (US) | 1994-07-12 | — | — | US | claimed |