Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 8/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.64 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.64 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.64 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 4/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689613 | 0.98 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10450203 | 0.98 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10450207 | 0.98 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10451801 | 0.98 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9745419 | 0.98 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL5691575 | 0.98 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL5691935 | 0.98 | S1PR2 (0.68) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9745857 | 0.93 | S1PR2 (0.55) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL5689630 | 0.90 | S1PR2 (0.59) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL21503939 | 0.84 | S1PR2 (0.62) | S1PR2S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664068-A2 | PROCESS FOR THE PREPARATION OF N-PHOSPHONO-METHYLGLYCINE AND DERIVATIVES THEREOF | Monsanto Technology, LLC (US) | 2006-06-07 | — | — | EP | claimed |
| US-20050054871-A1 | Process for the preparation of N-phosphonomethylglycine and derivatives thereof | MONSANTO TECHNOLOGY LLC | 2005-03-10 | — | — | US | claimed |
| WO-2005019230-A2 | PROCESS FOR THE PREPARATION OF N-PHOSPHONO-METHYLGLYCINE AND DERIVATIVES THEREOF | MONSANTO TECHNOLOGY LLC (US) | 2005-03-03 | — | — | WO | claimed |
| EP-0537786-B1 | Preparation of N-acylaminomethylphosphonic acid | SHOWA DENKO KK (JP) | 1998-01-21 | — | — | EP | claimed |
| US-5453537-A | Method for preparing an N-phosphonomethylglycine | SHOWA DENKO K.K. (JP) | 1995-09-26 | — | — | US | claimed |
| WO-1995013285-A1 | PROCESS FOR THE PREPARATION OF PHOSPHOROUS ACID/CARBOXYLIC ACID MIXED ANHYDRIDES AND ANHYDROUS PHOSPHOROUS ACID | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-18 | — | — | WO | claimed |
| EP-0341233-B1 | Process for the preparation of N-phosphonomethylglycine | MONSANTO CO (US) | 1995-03-22 | — | — | EP | claimed |
| US-5324855-A | Mixing an N-methylolamide with phosphorus trihalide in aprotic solvent, in presence of water, heating, then adding more water, efficiency, simplification | SHOWA DENKO K.K. (JP) | 1994-06-28 | — | — | US | claimed |
| US-5233080-A | Preparation of N-acylaminomethylphosphonic acids and aminomethylphosphonic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-03 | — | — | US | claimed |
| EP-0537786-A1 | Preparation of N-acylaminomethylphosphonic acid | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1993-04-21 | — | — | EP | claimed |
| US-5041627-A | Preparation of N-acyl-aminomethylphosphonates | MONSANTO COMPANY (US) | 1991-08-20 | — | — | US | claimed |
| EP-0370992-A2 | Preparation of N-acyl-aminomethylphosphonates | Monsanto Company (US) | 1990-05-30 | — | — | EP | claimed |
| EP-0341233-A2 | Process for the preparation of N-phosphonomethylglycine | Monsanto Company (US) | 1989-11-08 | — | — | EP | claimed |
| US-4851159-A | Process for the preparation of N- phosphonomethylglycine | MONSANTO COMPANY (US) | 1989-07-25 | — | — | US | claimed |
| JP-5112588-A | — | — | None | — | — | JP | disclosed |
| JP-1313487-A | — | — | None | — | — | JP | disclosed |
| JP-5112586-A | — | — | None | — | — | JP | disclosed |
| EP-0130008-B1 | METHOD FOR PREPARATION OF N-PHOSPHONOMETHYLGLYCINE | STAUFFER CHEMICAL COMPANY (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4261929-A | ONE STEP, FROM PHOSPHOROUS ACID, A NITRILE AND FORMALDEHYDE OR THEREACTION PRODUCT OF THE LATTER TWO | BENCKISER-KNAPSACK GMBH (DE) | 1981-04-14 | — | — | US | disclosed |
| US-4261929-A | ONE STEP, FROM PHOSPHOROUS ACID, A NITRILE AND FORMALDEHYDE OR THEREACTION PRODUCT OF THE LATTER TWO | BENCKISER-KNAPSACK GMBH (DE) | 1981-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054871-A1 | Process for the preparation of N-phosphonomethylglycine and derivatives thereof | PHOSPHO1, GNE, MPHOSPH6 | S1PR2 2735/4885S1PR1 2405/4885S1PR3 2245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.