SCHEMBL343526

SCHEMBL343526

FC(F)(F)C1(C(F)(F)F)OO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8561518 0.78
SCHEMBL14246470 0.67
SCHEMBL10078956 0.65
SCHEMBL375225 0.65
SCHEMBL1219152 0.65
SCHEMBL1950700 0.62
SCHEMBL9193872 0.62
SCHEMBL60538 0.62
SCHEMBL297507 0.58
SCHEMBL1463006 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595458-B1 Novel thiomarinol derivatives, and processes for their preparation SANKYO CO (JP) 1998-11-25 EP claimed
US-5395953-A Method of preparing hydrindane compounds and hydrindane-related compounds DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1995-03-07 US claimed
EP-0595458-A1 Novel thiomarinol derivatives, and processes for their preparation SANKYO COMPANY LIMITED (JP) 1994-05-04 EP claimed
EP-0594229-A1 Method of preparing hydrindane compounds and hydrindane-related compounds DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1994-04-27 EP claimed
EP-0453275-A1 Process for producing epoxy compound NIPPON OIL CO. LTD. (JP) 1991-10-23 EP claimed
JP-6206844-A None JP disclosed
CN-119630643-A Process and intermediate compounds for the preparation of 6-substituted-1- (2H) -isoquinolinones 瓦洛健康公司 2025-03-14 CN disclosed
US-9586899-B2 Synthetic process for aminocyclohexyl ether compounds CARDIOME PHARMA CORP. (CA) 2017-03-07 US disclosed
US-RE46234-E1 Tissue adhesive and sealant comprising polyglycerol aldehyde ACTAMAX SURGICAL MATERIALS, LLC (US) 2016-12-13 US disclosed
US-20150336887-A1 SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS CORREVIO CANADA CORP. (CA) 2015-11-26 US disclosed
US-20150336887-A1 SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS CORREVIO CANADA CORP. (CA) 2015-11-26 US disclosed
US-9115081-B2 Synthetic process for aminocyclohexyl ether compounds CARDIOME PHARMA CORP. (CA) 2015-08-25 US disclosed
EP-0595458-B1 Novel thiomarinol derivatives, and processes for their preparation SANKYO CO (JP) 1998-11-25 EP disclosed
US-5399711-A Bactericides, antimycoplasma agent, from Alteromonas SANKYO COMPANY, LIMITED (JP) 1995-03-21 US disclosed
US-5395953-A Method of preparing hydrindane compounds and hydrindane-related compounds DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1995-03-07 US disclosed
JP-H06206844-A PREPARATION OF HYDROINDANE AND ITS DERIVATIVE DUPHAR INTERNATL RES BV 1994-07-26 JP disclosed
EP-0595458-A1 Novel thiomarinol derivatives, and processes for their preparation SANKYO COMPANY LIMITED (JP) 1994-05-04 EP disclosed
EP-0594229-A1 Method of preparing hydrindane compounds and hydrindane-related compounds DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1994-04-27 EP disclosed
EP-0453275-A1 Process for producing epoxy compound NIPPON OIL CO. LTD. (JP) 1991-10-23 EP disclosed
EP-0370946-A2 Method of producing epoxide compounds CIBA-GEIGY AG (CH) 1990-05-30 EP disclosed