Benzonitrile

Benzonitrile

SCHEMBL343530

N#Cc1ccccc1.N#Cc1ccccc1.[Pd]

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.93
MAOB P27338 4/20 0.56
MAOA P21397 3/20 0.56
APP P05067 1/20 0.50
ALDH1A1 P00352 3/20 0.48
CYP2A6 P11509 2/20 0.48
CA12 O43570 1/20 0.48
CA2 P00918 1/20 0.48
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
HDAC8 Q9BY41 2/20 0.43
MAPT P10636 3/20 0.43
ENPP2 Q13822 2/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzonitrile SCHEMBL2708030 1.00
Benzonitrile SCHEMBL4272158 1.00 TSHR (0.93) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL3650085 0.97 TSHR (0.88) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL3082428 0.97 TSHR (0.88) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL6072015 0.97 TSHR (0.88) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL6071819 0.97 TSHR (0.88) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL11044747 0.97
Benzonitrile SCHEMBL6640 0.97
Benzonitrile SCHEMBL21752925 0.97
Benzonitrile SCHEMBL9464940 0.97 TSHR (1.00) TSHRMAOBMAOAAPPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184719-A Synthesis method of beta glucose thioglycoside and application of beta glucose thioglycoside in pharmacy 三峡大学 2024-06-14 CN claimed
CN-116457380-A Improved polycycloolefin compositions having stable shelf life and capable of bulk polymerization 普罗米鲁斯有限责任公司 2023-07-18 CN claimed
CN-116368165-A Polycyclic olefin composition for low loss films with improved thermal properties 普罗米鲁斯有限责任公司 2023-06-30 CN claimed
CN-110204558-B Synthesis of cephalosporin compounds 默沙东公司 2022-05-06 CN claimed
CN-111875637-B Phosphine ligand and synthesis method and application thereof 中国科学院兰州化学物理研究所 2022-03-15 CN claimed
CN-112368286-A Synthesis of coelenterazine 国际纸业公司 2021-02-12 CN claimed
CN-111875637-A Phosphine ligand and synthesis method and application thereof 中国科学院兰州化学物理研究所 2020-11-03 CN claimed
EP-3180347-B1 SYNTHESIS OF CEPHALOSPORIN COMPOUNDS MERCK SHARP & DOHME (US) 2020-09-23 EP claimed
CN-107531614-B Preparation method of delogevir 迈兰实验室有限公司 2020-04-10 CN claimed
EP-3013848-B1 PROCESS FOR THE PREPARATION OF ABIRATERONE AND INTERMEDIATES THEREOF SCINOPHARM TAIWAN LTD (TW) 2018-10-17 EP claimed
EP-1708989-A1 VINYLCHLOROFORMATE-FREE SYNTHESIS OF VINYL AND ALLYL(THIO)CARBAMATES BAUSCH & LOMB INCORPORATED (US) 2006-10-11 EP claimed
WO-2005073181-A1 VINYLCHLOROFORMATE-FREE SYNTHESIS OF VINYL AND ALLYL(THIO)CARBAMATES BAUSCH & LOMB INCORPORATED (US) 2005-08-11 WO claimed
EP-1171406-B1 METHOD OF PRODUCING BIARYLS DEGUSSA (DE) 2004-04-21 EP claimed
EP-1233944-B1 COUPLING CONDENSATION SYNTHESIS OF HETEROCYCLES MORPHOCHEM AG (DE) 2004-03-31 EP claimed
EP-0758333-B1 INTERMEDIATES IN PHARMACEUTICAL CAMPTOTHECIN PREPARATION OSI PHARM INC (US) 2004-03-03 EP claimed
WO-2002022618-A1 METHOD FOR PREPARING CAMPTOTHECIN AND ITS DERIVATIVES AVENTIS PHARMA S.A. (FR) 2002-03-21 WO claimed
EP-0510711-B1 Processes and compositions for electroless metallization CALVERT JEFFREY M (US) 2001-06-27 EP claimed
EP-0799195-B1 PROCESS FOR THE PREPARATION OF AROMATIC O-SULFOCARBOXYLIC ACIDS AND SULFONYLUREAS NOVARTIS AG (CH) 1999-04-14 EP claimed
EP-0407256-B1 PROCESS FOR OBTAINING NUCLEOPHILIC SUBSTITUTIONS RHONE-POULENC SANTE (FR) 1993-05-19 EP claimed
EP-0043485-B1 METHOD OF ACTIVATING SURFACES FOR ELECTROLESS PLATING BAYER AG (DE) 1985-05-15 EP claimed