Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26799878 | 0.89 | AR (0.74) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL12463531 | 0.85 | AR (0.71) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL4789704 | 0.83 | AR (0.63) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL5530939 | 0.82 | AR (0.65) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL1635879 | 0.81 | AR (0.79) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL24863637 | 0.81 | AR (0.68) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL1635802 | 0.81 | AR (0.73) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL1637447 | 0.80 | AR (1.00) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL23378210 | 0.80 | AR (1.00) | ARGAAHTTPRKAG1PRKAA2 | |
| SCHEMBL1636632 | 0.80 | AR (0.66) | ARGAAHTTPRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324095-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING AMYLOID-BETA PROTEIN ACCUMULATION | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-23 | — | — | US | disclosed |
| EP-2246334-A1 | MEDICINAL COMPOSITION FOR INHIBITING AMYLOID- PROTEIN DEPOSITION | Sumitomo Chemical Company, Limited (JP) | 2010-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324095-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING AMYLOID-BETA PROTEIN ACCUMULATION | APP, PSEN1, APBA1 | AR 3720/4885GAA 173/4885HTT 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.