Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 12/20 | 0.65 |
| ▸ | SCN1A | P35498 | 2/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.56 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252522 | 0.80 | SCN5A (0.70) | SCN5ASCN1ASCN2AGPR139 | |
| SCHEMBL252974 | 0.79 | SCN5A (1.00) | SCN5ASCN1ASCN2AGPR139 | |
| SCHEMBL253720 | 0.78 | SCN5A (0.77) | SCN5ASCN1ASCN2AGPR139 | |
| SCHEMBL15641728 | 0.78 | SCN5A (0.79) | SCN5ASCN1ASCN2AGPR139 | |
| SCHEMBL252755 | 0.77 | SCN5A (0.75) | SCN5ASCN1ASCN2AGPR139GRM2 | |
| SCHEMBL253051 | 0.76 | SCN5A (0.68) | SCN5ASCN1ASCN2AGPR139 | |
| SCHEMBL252119 | 0.76 | SCN5A (0.77) | SCN5ASCN1ASCN2AGPR139GRM2 | |
| SCHEMBL252856 | 0.76 | SCN5A (0.76) | SCN5ASCN1ASCN2AGPR139 | |
| SCHEMBL253931 | 0.75 | SCN5A (0.83) | SCN5ASCN1ASCN2AGPR139 | |
| SCHEMBL252480 | 0.74 | SCN5A (1.00) | SCN5ASCN1ASCN2AGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003392-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |