Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888551 | 0.93 | HCRTR1 (0.44) | HCRTR1HCRTR2NLRP3CYP1A2SMN1; SMN2 | |
| SCHEMBL15888606 | 0.91 | HCRTR1 (0.41) | HCRTR1HCRTR2NLRP3CYP1A2SMN1; SMN2 | |
| SCHEMBL10278249 | 0.89 | HCRTR1 (0.46) | HCRTR1HCRTR2NLRP3CYP1A2SMN1; SMN2 | |
| SCHEMBL3436269 | 0.88 | HCRTR1 (0.35) | HCRTR1HCRTR2KDM4EKMT2AMAPT | |
| SCHEMBL15888605 | 0.88 | HCRTR1 (0.45) | HCRTR1HCRTR2NLRP3CYP1A2SMN1; SMN2 | |
| SCHEMBL2078077 | 0.85 | PTGER1 (0.36) | HCRTR1HCRTR2KDM4EKMT2AMAPT | |
| SCHEMBL15888554 | 0.84 | HCRTR1 (0.44) | HCRTR1HCRTR2NLRP3CYP1A2KDM4E | |
| SCHEMBL2770990 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2NLRP3CYP1A2SMN1; SMN2 | |
| SCHEMBL28710578 | 0.84 | HCRTR1 (0.46) | HCRTR1HCRTR2NLRP3CYP1A2SMN1; SMN2 | |
| SCHEMBL15888574 | 0.83 | HCRTR1 (0.42) | HCRTR1HCRTR2NLRP3CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | HCRTR1 983/4885HCRTR2 605/4885NLRP3 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.