Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435110 | 0.92 | KDM4E (0.54) | DRD2DRD3TDP1SIGMAR1HTR3E | |
| SCHEMBL7445795 | 0.86 | POLB (0.75) | POLBLTA4HSMN1; SMN2ALDH1A1 | |
| SCHEMBL12661473 | 0.85 | POLB (0.73) | POLBDRD2DRD3LTA4HTDP1 | |
| SCHEMBL11360251 | 0.84 | TDP1 (0.74) | LTA4HTDP1NPSR1SIGMAR1CYP2C19 | |
| SCHEMBL11817599 | 0.82 | KDM4E (0.58) | POLBLTA4HTDP1SMN1; SMN2NPSR1 | |
| SCHEMBL17181753 | 0.81 | POLB (0.43) | POLBLTA4HTDP1SIGMAR1KDM4E | |
| SCHEMBL2158197 | 0.81 | KDM4E (0.60) | LTA4HTDP1SIGMAR1CYP2C19KDM4E | |
| SCHEMBL5319656 | 0.81 | KDM4E (0.70) | POLBTDP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28311407 | 0.81 | TSHR (0.72) | LTA4HTDP1SMN1; SMN2SIGMAR1CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL4267670 | 0.80 | KDM4E (0.68) | POLBTDP1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | claimed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | claimed |
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | claimed |
| CN-110128369-A | Benzo [d] isothiazole -3 (2H) -one derivative and its preparation method and application | 东南大学 | 2019-08-16 | — | — | CN | disclosed |
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | disclosed |
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | disclosed |
| US-8163907-B2 | Dihydropyridine calcium antagonist compounds, preparation methods, and medical uses thereof | COSUNTER PHARMACEUTICAL COMPANY (CN) | 2012-04-24 | — | — | US | disclosed |
| US-8163907-B2 | Dihydropyridine calcium antagonist compounds, preparation methods, and medical uses thereof | COSUNTER PHARMACEUTICAL COMPANY (CN) | 2012-04-24 | — | — | US | disclosed |
| US-20110201811-A1 | DIHYDROPYRIDINE CALCIUM ANTAGONIST COMPOUNDS, PREPARATION METHODS, AND MEDICAL USES THEREOF | COSUNTER PHARMACEUTICAL COMPANY (CN) | 2011-08-18 | — | — | US | disclosed |
| US-20110201811-A1 | DIHYDROPYRIDINE CALCIUM ANTAGONIST COMPOUNDS, PREPARATION METHODS, AND MEDICAL USES THEREOF | COSUNTER PHARMACEUTICAL COMPANY (CN) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201811-A1 | DIHYDROPYRIDINE CALCIUM ANTAGONIST COMPOUNDS, PREPARATION METHODS, AND MEDICAL USES THEREOF | RYR1, CACNA1E, CACNA1C | POLB 4761/4885DRD2 229/4885DRD3 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.