Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436633 | 0.91 | SLC18A3 (0.64) | SLC18A3ADRB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3436350 | 0.87 | SLC18A3 (0.54) | SLC18A3ADRB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3436351 | 0.87 | SLC18A3 (0.54) | SLC18A3ADRB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3436349 | 0.87 | SLC18A3 (0.54) | SLC18A3ADRB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3436355 | 0.84 | SLC18A3 (0.53) | SLC18A3ADRB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3436638 | 0.84 | SLC18A3 (0.53) | SLC18A3ADRB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3436329 | 0.80 | SLC18A3 (0.59) | SLC18A3ADRB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3435997 | 0.79 | GAA (0.57) | SLC18A3PBRM1NOTUMKMT2AMEN1 | |
| SCHEMBL3550794 | 0.79 | KMT2A (0.51) | SLC18A3ADRB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3436335 | 0.78 | SLC18A3 (0.54) | SLC18A3ADRB1PBRM1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | SLC18A3 1714/4885ADRB1 37/4885PBRM1 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.