Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CALML3 | P27482 | 1/20 | 0.43 |
| ▸ | SDHA | P31040 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393559 | 0.87 | MAOB (0.51) | MAOBMAOAKDM4EMAPTLMNA | |
| SCHEMBL3396930 | 0.84 | KDM4E (0.45) | MAOBMAOAKDM4EMAPTLMNA | |
| SCHEMBL13101197 | 0.78 | MAOB (0.47) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7950993 | 0.76 | MAOB (0.65) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7950997 | 0.76 | MAOB (0.65) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL3394870 | 0.75 | MAOB (0.45) | MAOBMAOAMAPTLMNAPTGS1 | |
| SCHEMBL5950151 | 0.75 | MAOB (0.63) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5949838 | 0.75 | MAOB (0.65) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL14448271 | 0.75 | MAOB (0.65) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5949842 | 0.75 | MAOB (0.65) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170874-A2 | NOVEL COMPOUNDS AND THEIR USE | Orchid Research Laboratories Limited (IN) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009001192-A2 | NOVEL COMPOUNDS AND THEIR USE | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-12-31 | — | — | WO | disclosed |