SCHEMBL3437333

SCHEMBL3437333

CCCCCC1CCC(C2CCC(c3ccc(OCC)c(F)c3F)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
GAA P10253 2/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
OPRL1 P41146 7/20 0.32
HPGD P15428 2/20 0.32
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM1A O60341 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15203896 1.00 MAPT (0.34) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL22277339 1.00 MAPT (0.34) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL423545 1.00 MAPT (0.34) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL8452731 1.00 MAPT (0.34) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL8452717 1.00 MAPT (0.34) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL10091129 1.00 MAPT (0.34) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL22277435 0.99 GAA (0.34) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL19985180 0.99 GAA (0.36) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL19985215 0.99 GAA (0.36) MAPTGAAMEN1KMT2AOPRL1
SCHEMBL19985220 0.99 GAA (0.36) MAPTGAAMEN1KMT2AOPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
US-20230183572-A1 LIQUID CRYSTAL COMPOSITION WITH GOOD FREQUENCY DEPENDENCE AND LIQUID CRYSTAL DISPLAY ELEMENT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2023-05-02 US disclosed
US-11466211-B2 Liquid crystal composition and liquid crystal display element including the same DIC CORPORATION (JP) 2022-10-11 US disclosed
US-20050056812-A1 Fluorinated heterocycles and their use in liquid-crystal mixtures MERCK PATENT GMBH (DE) 2005-03-17 US disclosed
US-5980778-A STABILITY, COMPATIBILITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0768361-A1 Liquid crystal composition and liquid crystal display element comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-04-16 EP disclosed
EP-0357727-B1 2,3-DIFLUOROBENZENE DERIVATIVES AND THEIR USE AS COMPONENTS OF LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 1993-11-24 EP disclosed
US-5236620-A 2,3-DIFLUOROBENZENE DERIVATIVES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-08-17 US disclosed
EP-0364538-B1 DIFLUOROBENZOL DERIVATIVES MERCK PATENT GmbH (DE) 1992-05-06 EP disclosed
EP-0364538-A1 DIFLUOROBENZOL DERIVATIVES. MERCK PATENT GMBH (DE) 1990-04-25 EP disclosed
EP-0357727-A1 2,3-DIFLUOROBENZENE DERIVATIVES AND THEIR USE AS COMPONENTS OF LIQUID CRYSTAL MEDIA. MERCK PATENT GMBH (DE) 1990-03-14 EP disclosed
WO-1989008689-A1 2,3-DIFLUOROBENZENE DERIVATIVES AND THEIR USE AS COMPONENTS OF LIQUID CRYSTAL MEDIA MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
WO-1989008633-A1 DIFLUOROBENZOL DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 MAPT 1064/4885GAA 4790/4885MEN1 3631/4885
US-20050056812-A1 Fluorinated heterocycles and their use in liquid-crystal mixtures CHRM1, SCO2, CHRM2 MAPT 3342/4885GAA 4835/4885MEN1 121/4885
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same SKP1, PKN1, KTN1 MAPT 1484/4885GAA 4728/4885MEN1 2210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.