SCHEMBL3437360

SCHEMBL3437360

CCCCC1CCC(C2CCC(c3ccc(OC(F)(F)F)cc3)CC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.42
RCOR1 Q9UKL0 1/20 0.42
CYP2C9 P11712 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
EPHX2 P34913 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ESR2 Q92731 1/20 0.37
LIPE Q05469 1/20 0.37
RAB9A P51151 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
TSHR P16473 1/20 0.36
DRD2 P14416 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4798854 1.00 KDM1A (0.42) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL4798875 1.00 KDM1A (0.42) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL5352855 0.96 KDM1A (0.41) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL5352864 0.96 KDM1A (0.41) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL3437355 0.96 KDM1A (0.41) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL8407553 0.96 KDM1A (0.45) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL9061117 0.96 KDM1A (0.45) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL9061171 0.95 KDM1A (0.40) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL9062074 0.95 KDM1A (0.40) KDM1ARCOR1CYP2C9MEN1KMT2A
SCHEMBL9061929 0.95 KDM1A (0.40) KDM1ARCOR1CYP2C9MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502407-B1 Nematic liquid-crystal composition for active matrix application SHARP KK (JP) 1996-02-07 EP claimed
US-5324449-A Substituted phenyl trifluoromethyl ethers MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-06-28 US claimed
US-5279763-A Nematic liquid-crystal composition for active matrix application MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-01-18 US claimed
EP-0334911-B1 SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS MERCK PATENT GmbH (DE) 1993-02-10 EP claimed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
US-20230167363-A1 LIQUID CRYSTAL COMPOSITION CONTAINING BENZOCHROMENE COMPOUND AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-06-01 US disclosed
US-11053441-B2 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-07-06 US disclosed
US-10941344-B2 Liquid crystal cell LG CHEM, LTD. 2021-03-09 US disclosed
US-20200123443-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-04-23 US disclosed
EP-2808375-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT PRODUCED USING SAME DAINIPPON INK & CHEMICALS (JP) 2020-01-22 EP disclosed
US-10457869-B2 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2019-10-29 US disclosed
EP-0438547-A1 SUPER-TWIST LIQUID CRYSTAL DISPLAY. MERCK PATENT GMBH (DE) 1991-07-31 EP disclosed
WO-1991010716-A1 MATRIX LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-07-25 WO disclosed
WO-1991002779-A1 LIQUID CRYSTALLINE MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-07 WO disclosed
EP-0414048-A2 Matrix-liquid crystal display MERCK PATENT GmbH (DE) 1991-02-27 EP disclosed
WO-1991000898-A1 SUPER-TWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-01-24 WO disclosed
EP-0394419-A1 MATRIX LIQUID CRYSTAL DISPLAY. MERCK PATENT GMBH (DE) 1990-10-31 EP disclosed
WO-1990004623-A1 MATRIX LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed
EP-0365962-A1 Matrix-type liquid-crystal display MERCK PATENT GmbH (DE) 1990-05-02 EP disclosed