SCHEMBL3438372

SCHEMBL3438372

COc1cccc(/C=C2/CCC(OC)CC2=O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
CASP3 P42574 1/20 0.59
SENP8 Q96LD8 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
SENP6 Q9GZR1 1/20 0.59
HSP90AA1 P07900 1/20 0.56
CCR6 P51684 1/20 0.56
EGFR P00533 5/20 0.54
MAPT P10636 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
PKM P14618 1/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
XDH P47989 4/20 0.49
APP P05067 1/20 0.46
MAOB P27338 2/20 0.46
MAOA P21397 1/20 0.46
PIM1 P11309 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3438373 1.00 NPC1 (0.59) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3438055 0.90 NPC1 (0.56) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3438058 0.90 NPC1 (0.56) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3438209 0.89 NPC1 (0.56) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3438210 0.89 NPC1 (0.56) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3438065 0.88 NPC1 (0.55) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3438066 0.88 NPC1 (0.55) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3437930 0.86 NPC1 (0.60) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3437931 0.86 NPC1 (0.60) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3438492 0.84 NPC1 (0.56) NPC1RAB9AHSP90AA1CCR6EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807856-B2 Process for production of 2-Benzylphenol compound IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2010-10-05 US disclosed
US-20080194882-A1 Process For Production of 2-Benzylphenol Compound IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2008-08-14 US disclosed
EP-1810957-A1 METHOD FOR PRODUCING 2-BENZYLPHENOL COMPOUND Ihara Chemical Industry Co., Ltd. (JP) 2007-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194882-A1 Process For Production of 2-Benzylphenol Compound CYP1B1, CYP4B1, CYP1A1 NPC1 4280/4885RAB9A 1012/4885CASP3 1125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.