Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 5/20 | 0.40 |
| ▸ | F10 | P00742 | 12/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118663 | 0.93 | BDKRB1 (0.37) | BDKRB1F10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3440543 | 0.90 | BDKRB1 (0.40) | BDKRB1 | |
| SCHEMBL12012120 | 0.85 | BDKRB1 (0.39) | BDKRB1F10 | |
| SCHEMBL3440246 | 0.84 | BDKRB1 (0.57) | BDKRB1 | |
| SCHEMBL12047239 | 0.80 | BDKRB1 (0.38) | BDKRB1F10 | |
| SCHEMBL3440165 | 0.79 | BDKRB1 (0.56) | BDKRB1 | |
| SCHEMBL13063132 | 0.77 | F10 (0.36) | F10NR1H4 | |
| SCHEMBL13063102 | 0.76 | BDKRB1 (0.38) | BDKRB1F10NR1H4 | |
| SCHEMBL3440397 | 0.76 | BDKRB1 (0.47) | BDKRB1 | |
| SCHEMBL13063111 | 0.76 | BDKRB1 (0.38) | BDKRB1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-A1 | Analgetic phenylsulphonamides | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |