Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.67 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319627 | 1.00 | HRH3 (0.67) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL7329891 | 0.98 | HRH3 (0.64) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL30596544 | 0.96 | HRH3 (0.67) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL13577677 | 0.94 | HRH3 (0.69) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL22375323 | 0.86 | CXCR4 (0.58) | HRH3HRH4MEN1KMT2ASIGMAR1 | |
| SCHEMBL8533991 | 0.86 | HRH3 (0.58) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL8533993 | 0.86 | HRH3 (0.58) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL23269704 | 0.84 | LSS (0.57) | HRH3HRH4ALDH1A1KDM4EMEN1 | |
| SCHEMBL8532860 | 0.84 | HRH3 (0.56) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL8532857 | 0.84 | HRH3 (0.56) | HRH3HRH4ALDH1A1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-A1 | Analgetic phenylsulphonamides | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |