⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043180 | 0.85 | GRM4 (0.37) | — | |
| SCHEMBL7259738 | 0.82 | — | — | |
| SCHEMBL10786116 | 0.80 | EPHX1 (0.48) | — | |
| SCHEMBL10145416 | 0.80 | EPHX1 (0.42) | — | |
| SCHEMBL1427216 | 0.78 | GRM4 (0.36) | — | |
| SCHEMBL27365365 | 0.78 | — | — | |
| SCHEMBL14642148 | 0.77 | GRM4 (0.34) | — | |
| SCHEMBL14917578 | 0.75 | CYP2D6 (0.37) | — | |
| SCHEMBL15747088 | 0.75 | — | — | |
| SCHEMBL841701 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397730-A | Tertiary amine composition and method for making the composition | 气体产品与化学公司 | 2017-02-15 | — | — | CN | claimed |
| US-20230190751-A1 | 6-6 Fused Bicyclic Heteroaryl Compounds and their Use as LATS Inhibitors | NOVARTIS INSTITUTE FOR FUNTIONAL GENOMICS, INC., DBA GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION | 2023-06-22 | — | — | US | disclosed |
| WO-2022262789-A1 | ANTITUMOR COMPOUND AND USE THEREOF | 明慧医药（杭州）有限公司 | 2022-12-22 | — | — | WO | disclosed |
| US-11458138-B2 | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | NOVARTIS AG (CH) | 2022-10-04 | — | — | US | disclosed |
| US-20210154191-A1 | METHODS OF TREATMENT OF CANCER | PANO THERAPEUTICS, INC. (US) | 2021-05-27 | — | — | US | disclosed |
| US-20190051432-A1 | ELECTRICAL CHARACTERISTICS OF SHIELDED ELECTRICAL CABLES | 3M INNOVATIVE PROPERTIES COMPANY | 2019-02-14 | — | — | US | disclosed |
| CN-104302684-B | Tertiary amine composition and method for producing said composition | 气体产品与化学公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106397730-A | Tertiary amine composition and method for making the composition | 气体产品与化学公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-104302684-A | Tertiary amine composition and method for producing said composition | AIR PROD & CHEM | 2015-01-21 | — | — | CN | disclosed |
| CN-104245767-A | Polyurethane foam production process, pre-mix, formulation, and product | AIR PROD & CHEM | 2014-12-24 | — | — | CN | disclosed |
| CN-103946260-A | Processes, products, and compositions having tetraalkylguanidine salt of aromatic carboxylic acid | AIR PROD & CHEM | 2014-07-23 | — | — | CN | disclosed |
| US-20120015901-A1 | METHODS AND PREPARATIONS FOR PROTECTING CRITICALLY ILL PATIENTS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2012-01-19 | — | — | US | disclosed |
| EP-2341886-A1 | ANTIMICROBIAL N-CHLORINATED COMPOSITIONS | NovaBay Pharmaceuticals, Inc. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010113834-A1 | PYRIMIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010054269-A1 | ANTIMICROBIAL N-CHLORINATED COMPOSITIONS | NOVABAY PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| CN-1501933-A | Novel 10-cyclohexenylpyrrolobenzodiazepines * -3-carboxamides and derivatives thereof; tocolytic oxytocin receptor antagonists | — | 2004-06-02 | — | — | CN | disclosed |
| EP-0796646-B1 | Method for the removal of carbon dioxide present in gases and absorbent | KANSAI ELECTRIC POWER CO (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-6051161-A | BRINGING A CARBON DIOXIDE CONTAINING GAS INTO CONTACT WITH AN AQUEOUS SOLUTION CONTAINING AT LEAST ONE AMINE COMPOUND; REDUCTION IN THERMAL ENERGY REQUIRED FOR REGENERATION OF THE AQUEOUS SOLUTION | THE KANSAI ELECTRIC POWER CO., INC. (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0796646-A1 | Method for the removal of carbon dioxide present in gases and absorbent | THE KANSAI ELECTRIC POWER CO., INC. (JP) | 1997-09-24 | — | — | EP | disclosed |