SCHEMBL3441225

SCHEMBL3441225

Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(C(=O)Nc2ccc(F)cc2)c1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4903090 0.90 CYP2C9 (0.62) CYP2C9
SCHEMBL13122948 0.89 CYP2C9 (0.61) CYP2C9
SCHEMBL4975360 0.88 CYP2C9 (0.56) CYP2C9
SCHEMBL2689198 0.87 CYP2C9 (0.59) CYP2C9
SCHEMBL398913 0.86 CYP2C9 (0.54) CYP2C9
SCHEMBL13643827 0.86 CYP2C9 (0.63) CYP2C9
SCHEMBL4898573 0.85 CYP2C9 (0.57) CYP2C9
SCHEMBL404183 0.84 CYP2C9 (0.61) CYP2C9
SCHEMBL1014694 0.84 CYP2C9 (0.61) CYP2C9
SCHEMBL3955995 0.83 CYP2C9 (0.60) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010133312-A1 HALOGEN-SUBSTITUTED COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-11-25 WO disclosed
EP-2253617-A1 Halogenated compounds as pesticides Bayer CropScience AG (DE) 2010-11-24 EP disclosed
EP-2253617-A1 Halogenated compounds as pesticides Bayer CropScience AG (DE) 2010-11-24 EP disclosed