⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3526636 | 0.98 | — | — | |
| SCHEMBL978923 | 0.64 | — | — | |
| SCHEMBL721757 | 0.61 | — | — | |
| SCHEMBL15440826 | 0.58 | — | — | |
| SCHEMBL21900123 | 0.58 | — | — | |
| SCHEMBL5048266 | 0.58 | — | — | |
| SCHEMBL11536305 | 0.57 | — | — | |
| SCHEMBL11530755 | 0.57 | HDAC4 (0.31) | — | |
| SCHEMBL8210519 | 0.56 | — | — | |
| SCHEMBL11536961 | 0.54 | FFAR3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928887-B1 | METHODS OF PREPARING QUINOLONE ANALOGS | SENHWA BIOSCIENCES INC (TW) | 2014-12-17 | — | — | EP | disclosed |
| US-7834180-B2 | Methods of preparing quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-11-16 | — | — | US | disclosed |
| US-7816406-B2 | Quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816524-B2 | Methods of preparing quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20090082565-A1 | METHODS OF PREPARING QUINOLONE ANALOGS | CYLENE PHARMACEUTICALS, INC. (US) | 2009-03-26 | — | — | US | disclosed |
| EP-1928887-A1 | METHODS OF PREPARING QUINOLONE ANALOGS | Cylene Pharmaceuticals, Inc. (US) | 2008-06-11 | — | — | EP | disclosed |
| EP-1802306-A2 | QUINOLONE ANALOG AS CELL PROLIFERATION INHIBITORS | Cylene Pharmaceuticals, Inc. (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2007019295-A1 | METHODS OF PREPARING QUINOLONE ANALOGS | CYLENE PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070032652-A1 | Methods of preparing quinolone analogs | SENHWA BIOSCIENCES, INC. (TW) | 2007-02-08 | — | — | US | disclosed |
| US-20060074089-A1 | Quinolone analogs | SENHWA BIOSCIENCES, INC. (TW) | 2006-04-06 | — | — | US | disclosed |
| WO-2006034113-A2 | QUINOLONE ANALOGS AS CELL PROLIFERATION INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2006-03-30 | — | — | WO | disclosed |