Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA3 | P07451 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | CA6 | P23280 | 2/20 | 0.61 |
| ▸ | DPP4 | P27487 | 2/20 | 0.61 |
| ▸ | CA5A | P35218 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3446064 | 1.00 | HCAR2 (0.61) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL3446068 | 1.00 | HCAR2 (0.61) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL14081549 | 0.84 | HCAR2 (0.81) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL713717 | 0.84 | HCAR2 (0.81) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL68395 | 0.84 | HCAR2 (0.81) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL18662489 | 0.82 | HCAR2 (0.77) | HCAR2CA12AKR1B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL11835203 | 0.82 | HCAR2 (0.77) | HCAR2CA12AKR1B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL8378608 | 0.82 | HCAR2 (0.77) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL19449704 | 0.82 | HCAR2 (0.59) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL3445417 | 0.80 | HDAC2 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816386-B2 | Cinnamic, phenylpropiolic and phenylpropanoic acid derivatives useful as anti-tumor agents | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2010-10-19 | — | — | US | disclosed |
| US-20080194659-A1 | Cinnamic, Phenylpropiolic and Phenylpropanoic Acid Derivatives Useful as Anti-Tumor Agents | SIGMA-TAU FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194659-A1 | Cinnamic, Phenylpropiolic and Phenylpropanoic Acid Derivatives Useful as Anti-Tumor Agents | ABCC1, VHL, ABCB1 | HCAR2 28/4885CA12 863/4885AKR1B10 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.